Additionally, Keskin et al. identified NLRP3 polymorphisms as important biomarkers associated with bone resorption in the context of chronic otitis media [34], while Slezakova et al. detected a link between the NLRP3 rs4612666 polymorphism and recurrent aphthous stomatitis (RAS) incidence in a Czech cohort [35]. The gene discussed is NLRP3; the disease is chronic otitis media.