TP53 and leiomyosarcoma: WGS revealed 30 SNVs and one indel, including variants in TP53 (p.H193R; AF, 0.79) and RB1 (p.F839fs*10; AF, 0.81), which were both associated with loss of heterozygosity of the wildtype allele, a typical finding in leiomyosarcomas that show near-universal inactivation of TP53 and RB177.