Moreover, the frequencies of the TERT*(rs2736100; c.1574-3777G > T) variant revealed a statistical difference with increased risk of HCC compared to control subjects under recessive [OR = 1.84, 95% CI = 1.03–3.29, P-value = 0.039] model, (Table 3). This evidence concerns the gene TERT and hepatocellular carcinoma.