The expected and observed frequencies of the TERT*(rs2736100; c.1574-3777G > T) variant for cancer-free controls and HCC patients were in alignment with the Hardy–Weinberg equilibrium (HWE) [p-value > 0.05], while those of the TERT*(rs2736098; c.915G > A) variant were mismatched with HWE among HCC patients [p-value = 0.02], and this could be imputed to the higher frequency of the TERT (rs2736098*G/A) genotype. Here, TERT is linked to cancer.