Specifically, NFE2L2, NLRP3, ATP7A, FDX1, LIAS, LIPT1, LIPT2, DLD, MTF1, GLS, DBT, GCSH, and DLST were higher expressed in normal tissues compared with tumor samples, while CDKN2A, SLC31A1, ATP7B, and PDHB were higher expressed in breast cancer tissues (Table 1). The gene discussed is LIAS; the disease is breast cancer.