Specifically, NFE2L2, NLRP3, ATP7A, FDX1, LIAS, LIPT1, LIPT2, DLD, MTF1, GLS, DBT, GCSH, and DLST were higher expressed in normal tissues compared with tumor samples, while CDKN2A, SLC31A1, ATP7B, and PDHB were higher expressed in breast cancer tissues (Table 1). The gene discussed is NLRP3; the disease is neoplasm.