PDHB and breast cancer: Specifically, NFE2L2, NLRP3, ATP7A, FDX1, LIAS, LIPT1, LIPT2, DLD, MTF1, GLS, DBT, GCSH, and DLST were higher expressed in normal tissues compared with tumor samples, while CDKN2A, SLC31A1, ATP7B, and PDHB were higher expressed in breast cancer tissues (Table 1).