Then we analyzed the correlation between PTPN2 expression and stemness score, and tumor heterogeneity, like RNAss (RNA expression-based), EREG.EXPss (epigenetically regulated RNA expression-based), DNAss (DNA methylation-based), EREG-METHss (epigenetically regulated DNA methylation-based), DMPss (differentially methylated probes-based), ENHss (enhancer Elements/DNA methylation-based), TMB (tumor mutational burden), MATH, MSI (microsatellite instability), purity, ploidy, HRD, LOH, and NEO. Here, PTPN2 is linked to neoplasm.