We note that the recoded DENV2-rcCap-Env+rsCE clone had a lower infection rate in Aedes albopictus mosquitoes: when we used an infectious blood meal with a virus concentration of 2.5 x 107 PFU/ml, wildtype DENV2 could infect 29/30 mosquitoes, but DENV2-rcCap-Env+rsCE was only able to infect 24/30 mosquitoes (Fig 4E). Here, ERVW-1 is linked to infection.