Both ablation treatment arms containing liposomal preparations, RFA-lip-GM-CSF and RFA-BL, had increased CD11C+ and CD8+ and CD4+ lymphocytes infiltration in the synchronous non-ablated tumor at 7d compared to either RFA alone or sham treatment (p<0.05) (Fig 5A–5C). The gene discussed is CD8A; the disease is neoplasm.