KCNQ1 and familial long QT syndrome: In this issue of the journal, the Fetal LQTS Consortium presents an elegant study that informs the natural history of LQTS by expanding and refining the current understanding of FHR/GA dynamic in familial LQTS pregnancies, taking cohort, genotype, variant type/effect, and maternal β-blocker therapy into consideration.13 The authors used a multi-source identification to recruit an extensive cohort of 267 offspring from 164 LQTS families across eight countries, of which 60% inherited the familial LQTS-causative variant [LQT1 (KCNQ1, 82%), LQT2 (KCNH2, 13%), or LQT3 (SCN5A, 5%)].