CatL is also related to other pathologiessuch as liver fibrosis, diabetes, and kidney disorders.11−17 Lately, the interest in developing cathepsin L inhibitors has beenexpanded mainly due to its possible active role in viral infection.18 In this regard, CatL can serve as an importantmodulator of the entry of Severe Acute Respiratory Syndrome Coronavirus2 (SARS-CoV-2) into the host cell. Here, CTSL is linked to viral infectious disease.