RBM8A and microcephaly: In mice, depletion of Rbm8a revealed a microcephaly phenotype similar to the one observed in Magoh. Here, the neuronal loss is mainly observed in upper cortical layers, and reduced proliferation accompanied of premature differentiation of NPCs were found (Mao et al., 2015; Zou et al., 2015; Mao et al., 2016).