In mice, Citk deficiency is associated with cytokinesis defects, DSBs accumulation, and p53-dependent apoptosis, and overall impaired mouse neurogenesis leading to microcephaly (Di Cunto et al., 2000; Sarkisian et al., 2002; Bianchi et al., 2017; Iegiani et al., 2022). The gene discussed is TP53; the disease is microcephaly.