BRCA2 and microcephaly: On the other hand, biallelic hypomorphic mutations in BRCA2 have been associated to hypersensitivity to DNA damage and FA leading to the manifestation of microcephaly in affected patients (Weinberg-Shukron et al., 2019; Kennedy and D’Andrea, 2005; Frappart et al., 2007; Sharan et al., 1997).