The primary clinical symptoms are dermatological manifestations such as reddish pruritic rashes, erythematous maculopapular eruptions, mucosal lesions on the lip, nose, and exulcerations in the genital region and then fusion to form bullae or blisters, as well as the non-dermatological manifestation such as high fever, myalgia, conjunctivitis, CD8+ antibody positive, white blood cells, CRP, neutrophils and other inflammatory indicators increased leading to pain, unable to eat, loss of a large number of body fluids and electrolytes (26, 33). Here, CD8A is linked to conjunctivitis.