In this study, ITGA2+ cells density were found to be significantly correlated with CA-199 (P= 0.004), CEA (P=0.03), TNM stage (P= 0.037), lymph node metastasis (P= 0.001) and local invasion (P= 0.02), indicating its importance in the diagnosis and growth of pancreatic cancer. The gene discussed is ITGA2; the disease is metastatic malignant neoplasm in the lymph nodes.