The analysis of mRNA levels of these markers in cells incubated with various CMs using real-time PCR showed that Eto-CM and Oxa-CM in both A549wt and DLD1wt cells considerably elevated Aurka, Ki67 and MCM10 expression levels, whereas incubation in CMs from shHsp70 cells had no effect on the expression of the analyzed genes (Fig. 2G), further proving a critical role of Hsp70 in stimulating the regrowth of sparse tumor cell populations in vitro. This evidence concerns the gene MCM10 and neoplasm.