The results of the KEGG signaling pathway enrichment analysis indicated that the high expression group of P2RY6 was significantly enriched in pathways such as the IL-17 signaling pathway, cytokine-cytokine receptor interaction, inflammatory bowel disease, toll-like receptor signaling pathway, and NF-kappa B signaling pathway (Fig. 3A–B, all p < 0.01). This evidence concerns the gene IL17A and inflammatory bowel disease.