The results from Kaplan–Meier analysis revealed a significant correlation between high P2RY6 expression and a decline in overall survival (OS) for various cancer types, including CESC, BRCA, GBM, COAD, ESCA, KIRC, HNSC, KIRP, LIHC, LGG, LUAD, PAAD, PCPG (pheochromocytoma and paraganglioma), TGCT, THYM (thymoma), STAD, UCEC, and UVM (Supplementary Fig. 2, all p < 0.05). Here, P2RY6 is linked to pheochromocytoma.