Heat map of 45 significantly different immune cells in high-risk vs. low-risk groups, including CD8 + T cell, Neutrophil, Myeloid dendritic cell, M2 Macrophage, Tregs, Endothelial cell, Cancer-associated fibroblast, etc., was plotted in Fig. 10A (Wilcoxon test, P < 0.01). This evidence concerns the gene CD8A and cancer.