It could be seen that patients with positive lymph nodes had a higher risk score than those with lymph node metastasis negative via the Wilcox test, which meant that a higher risk score indicated a worse prognosis; whereas risk scores were not significantly different between the presence and absence of FGFR3, P53, RB1, or Ras mutation, distant metastasis, high grade (Fig. 7E, J). The gene discussed is TP53; the disease is metastatic malignant neoplasm in the lymph nodes.