Among all cell lines tested in this study, FGFR1 was highly expressed in EGFR + NSCLC NCI-H1650, HCC827, NCI-H1975, and HER2 + BC HCC1569 cells and BRAF+melanoma RPMI-7951, IGR-39, and SK-MEL-3 cells, and FGF2 was highly expressed in NCI-H1650, HCC827, HCC1569, RPMI-7951, and IGR-39 cells (Fig. 5a). This evidence concerns the gene FGF2 and melanoma.