In order to see whether the observed effects of DMF were specific to HMECs, we also tested glucose uptake and glutamine oxidation in different cell lines treated with DMF, including macro- and mesovascular ECs (BAECs and HUVECs), two breast adenocarcinoma cell lines (MDA-MB-231 and MCF7), a cervix adenocarcinoma cell line (HeLa) and fibroblasts (HGF), in order to cover non-microvascular ECs, different tumor cell lines and a non-transformed cell line different from endothelium. The gene discussed is HGF; the disease is breast adenocarcinoma.