To determine whether the loss of CCZ1 may affect entry mediated by filovirus glycoproteins, wild-type and CCZ1 mutant A549 cells were infected with VSVΔG/MARVGP at a MOI of 20, fixed at an early time point post infection (6 h), and assessed for intracellular distribution of VSV-M protein. Here, CCZ1 is linked to infection.