In addition, Beaudin et al. also found that VKORC1 and VKORC1L1 were highly expressed in triple-negative breast cancer (TNBC) cell lines and advanced breast cancer tissues, and promoted the growth of TNBC cells, and the expression of glutamate-modified proteins through vitamin K1 synthesis75. The gene discussed is VKORC1; the disease is triple-negative breast carcinoma.