The following 11 B-ALL subtypes were included in this analysis, namely hyperdiploidy (n = 20), ETV6::RUNX1 (n = 11), TCF3::PBX1 (n = 5), KMT2A rearranged (n = 5), BCR::ABL1 (n = 3), BCR::ABL1-like (n = 4), ZNF384 (n = 3), PAX5alt (n = 2), TCF3::HLF (n = 1), hypodiploidy (n = 1), MEF2D (n = 1), and five cases with unclassified subtype, which were designated B-other. The gene discussed is RUNX1; the disease is acute lymphoblastic leukemia.