ALPL and urolithiasis: The GWAS studies published in 2007–2017 disclosed seven loci associated with propensity to the form of urinary stones, such as 5q35,3 (rs11746443; rs12654812 in SLC34A1); 3q21.1 (rs7627468 in CASR); 13q14.1 (rs4142110 in DGKH); 21q22.13 (rs219780, rs199565725 in CLDN14); 7q14.3 (rs1000597, rs12669187 in AQP1); 7q34 (p.L530A in TRPV5) and 1p36.12 (rs1256328 in ALPL) [58].