Using all genes with logFC in each pathway, the GSEA further validated the activation of JAK-STAT signaling, NOD-like and Toll-like receptor signaling, and Apoptosis in TAAD patients, with a coinstantaneous inhabitation of Dilated cardiomyopathy, Cell adhesion molecules, Vascular smooth muscle contraction (Figure 2F and Supplementary Table 6). This evidence concerns the gene SOAT1 and dilated cardiomyopathy.