No significant difference was found between CD4 count under cART and the frequency of positive T-cell responses under cART in all 90 individuals, non-AIDS HIV-1 patients, and AIDS patients (Fig. 7D), whereas a trend of a positive association of ΔCD4 (CD4 count under cART minus CD4 count at pre-cART) with the frequency of positive T-cell responses under cART was found in AIDS patients (Fig. 7E). The gene discussed is CD4; the disease is AIDS.