Comparison of cytokine concentrations between MPN subtypes revealed a significant increase in TNFα and IL-12p70 in subjects with MF when compared to ET (Tukey’s test; TNFα P-adj <0.001 and IL-12p70 P-adj = 0.016) and PV (Tukey’s test; TNFα P-adj = 0.002 and IL-12p70 P-adj = 0.022, Fig. 5a). The gene discussed is TNF; the disease is myeloproliferative neoplasm.