According to current studies, polysaccharides act on PRRs and promote the maturation of DCs through various pathways such as PI3K/AKT, MAPK, NF-κB, and Dectin-1/Syk, specifically by increasing the expression of costimulatory molecules and MHC class molecules, weakening endocytosis, activating T cells, and increasing the secretion of pro-inflammatory cytokines, in addition to regulating the intracellular metabolism of DCs, thereby enhancing immune response and playing an important role in tumor invasion and improvement of tumor disease prognosis. This evidence concerns the gene NFKB1 and neoplasm.