Neurotrophic tyrosine receptor kinase 1, 2, and 3 (NTRK1, NTRK2, and NTRK3) genes encode for three tyrosine kinase receptors (TRKA, TRKB, and TRKC, respectively) and act as oncogenic drivers in a well-defined subgroup of cancers (1). This evidence concerns the gene NTRK1 and cancer.