NOD2 and colitis: However, other groups of mice followed until 12 days after the beginning of DSS treatment, exhibited a decrease of colon shortening in Nod2ΔLyzM mice in the recovery phase of 7 days after the end of DSS (Figure 2C), which is consistent with a less damaged colon based on histological sections at day 7 (Figures 2D, E), and suggesting that mice with NOD2 deletion in macrophages are less susceptible to acute colitis.