In 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis (HBP) in hamsters, DMBA-induced hamsters exhibited abnormally high expression of NF-KB-p65, IKKβ, c-Jun and c-Fos, which triggered signals for cancer cell proliferation. The gene discussed is NFKB1; the disease is cancer.