After applying the Bonferroni correction (Psmr < 2.08 × 10–6) and HEIDI threshold (PHEIDI > 0.01), a total of four SMR genes were identified: three SMR genes (AHI, MED24, and DDX5) with the European asthma-GWAS summary and one SMR gene (RPS26) with the Japanese asthma-GWAS summary (Additional File 2: Table S7). This evidence concerns the gene DDX5 and asthma.