AFP, alpha-fetoprotein; ASA, American Society of Anesthesiologists; ALT, alanine aminotransferase; AST, aspartate transaminase; BCLC, Barcelona Clinic Liver Cancer; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; MVI, microvascular invasion. The gene discussed is AFP; the disease is hepatocellular carcinoma.