Additionally, uPAR is not expressed uniformly across cell types or cancer cells as it has been found to be most highly expressed in cancer cells located on the invasive front of bladder tumors compared to cells located within the tumor core in the study by Dohn et al., with myofibroblasts having the greatest expression rates among cell types, as measured by immunohistochemistry [30]. Here, PLAUR is linked to urinary bladder neoplasm.