Student’s t-test and ROC curve was performed to compare the control and cancer groups; 5 (CCT3, PCMT1, TKT, TOMM34, UBA1) and 2 proteins (CCT3 and TOMM34) were satisfied with the significant differences rule (Student’s t-test: p ≤ 0.05, AUC: AUC value ≥ 0.7) in control versus cancer (grade 4) and control versus cancer (grade 3and 4), respectively. The gene discussed is UBA1; the disease is cancer.