PARP1high acute myeloid leukaemia, which lacked NKG2D ligands but showed functional stemness characteristics, initiated serially re-transplantable leukaemia, whereas transfer of polyclonal NK cells, after treatment with PARP1 inhibitors which restored NKG2D ligand expression, suppressed leukaemogenesis46. This evidence concerns the gene KLRK1 and leukemia.