The deficiency of eEF2K promotes a pro-inflammatory microenvironment, which is closely linked to autoimmune disorders like rheumatoid arthritis—a condition characterized by CD4+ T cell hyperactivation,33,34 we next delved into whether the absence of eEF2K in CD4+ T cells has any influence on the development of rheumatoid arthritis. Here, CD4 is linked to rheumatoid arthritis.