Further research may provide more insights into the complex interplay between eEF2K, STAT3, and CD4+ T cells in autoimmune disorders.45 Our work provides a link between the loss of eEF2K in CD4+ T cells leading to a shift towards the Th17 profile and the development of inflammation-related diseases, including rheumatoid arthritis. This evidence concerns the gene STAT3 and rheumatoid arthritis.