These in vitro results were in line with a recent study concluding that EMT of colon cancer can be suppressed by down‐regulating FOXA2 with a decrease in E‐cadherin and Vimentin.[26] Therefore, we assumed that the regulatory effects of FOXA2 on EMT and metastasis events are largely dependent on the different types of cancer cells, thus requiring more studies for specific tumor types. This evidence concerns the gene FOXA2 and malignant colon neoplasm.