FOXA2 and neoplasm: For instance, FOXA2 is a driving factor in promoting neuroendocrine prostate cancer.[43] Additionally, FOXA2 suppression is involved in afatinib‐inhibited stemness and tumor spheres of pancreatic cancer stem cells.[44] Thus, the effects of FOXA2 on tumorigenesis are complicated without a thorough understanding, which may be associated with the different types of cancer cells.