As shown in Figure 2E, increased E‐Cadherin and decreased N‐cadherin, Vimentin, Fibronectin, MMP13, and TGF‐β1 were detected in CRC cells with FOXA2 deletion compared with the sh‐NC group; however, opposite expression trends were observed in HCT‐116 and SW480 cells over‐expressing FOXA2. This evidence concerns the gene CDH1 and colorectal carcinoma.