CD274 and neoplasm: Furthermore, self‐tolerance hijacked by TNBC was then relieved: tumor immune microenvironment, including PD‐L1 expression, immune cells and cytokines, was retrograded to the status as it should be before the coevolution.[24, 26, 46, 47] Consequently, immunosuppression was removed, and immune cells were recruited through ICD of tumor cells and rushed deep into the retrograded tumor environment to burst systemic immunoresponses to sweep tumor cells away and generate immune memory to curb tumor progression.