Furthermore, the disease-gene associations related to amyloidosis (Apolipoprotein E [APOE], C3, FGA, Transthyretin [TTR], and Serum amyloid P-component [APCS or SAMP]) showed significant enrichment (FDR = 2.66E-5) (Figure 4B). This evidence concerns the gene XPNPEP1 and amyloidosis.