MBOAT7 is as a membrane-bound O-acyltransferase that is involved in lipid metabolism, which overexpression in LUAD could predict poor prognosis [18]. PTDSS1 overexpression is also associated with poor prognosis, and may contribute to the aggressive behaviors of cancer cells by promoting proliferation, migration, and invasion, as well as suppressing immune functions [19]. This evidence concerns the gene PTDSS1 and cancer.