We observed that an increased number of plasma analytes were expressed at higher levels during early infection (T1), many of which were described in migration or recruitment (IL-16, IL-1 β, MCP-1, CX3CL1, and sFasL), differentiation (BCA-1 and IL-21), proliferation (CX3CL1), and activation (IL-21) of immune cells, including lymphocytes such as B cells, T cells and monocytes. The gene discussed is CX3CL1; the disease is infection.