IP-10 and I-TAC have been shown to be correlated with HIV-1 severity in humans as monocytes and dendritic cells (DCs) produce IP-10 in response to HIV-1 infection and promote latent infection in resting memory CD4 T cells by facilitating HIV entry and integration (31, –, 33). The gene discussed is CXCL10; the disease is disease arising from reactivation of latent virus.