In our study, we thoroughly analyzed RMD across different CKD stages and found that RMD (CD34 PPA-total and CD34 PPA-peritubular capillary) significantly increased (p < 0.05) during disease progression from CKD stages 1 to 2, followed by a gradual decline across CKD stages 2 to 5. The gene discussed is CD34; the disease is chronic kidney disease.