Another important fact for CRP—even when its precise form is not known—is that it can be rapidly and actively transported into the cell nuclei due to the presence of a nuclear localization sequence, and as it binds strongly to snRNPs both in vitro and in vivo, it is possibly involved in the clearance of these critical autoantigens; however, CRP was found to be protective against the formation of autoimmunity in mice, and such data suggest that CRP is perhaps capable of monitoring the expression of certain genes [128]. Here, CRP is linked to Autoimmunity.