As a result, undeniably, BMI is not applicable, which several studies take into account when assessing CRP in parallel with CVDs or other conditions, because even if obesity were always a prognostic factor for elevated CRP and poor outcomes, some people have normal BMI but consume high percentages of foods that boost acidosis, and as a result, biases arise in these studies (that report no BMI association with the analyzed medical condition). The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.