FCGR2B and acute kidney injury: Moreover, it was established that CRP exacerbates acute kidney injury in mice, and this was associated with the heightened renal accumulation of myeloid-derived cells with suppressor functions, with a research study revealing CRP’s ability to expand and trigger the increased FcγRIIb-independent production of iROS in these cells, as well as its ability to FcγRIIb-dependently enhance the T cell-suppressive action [154].