Furthermore, a meta-analysis found that Parkinson’s Disease (PD) is associated with an increase in CRP, which might be a risk factor for PD, and other data demonstrate that a higher baseline hsCRP may predict early idiopathic PD and poor prognosis—thus, subclinical systemic inflammations may accelerate neurodegeneration in PD—and, indeed, systemic inflammation in Lewy body diseases, particularly in PD, dementia is recorded. This evidence concerns the gene CRP and Parkinson disease.