CRP and systemic lupus erythematosus: The monomers’ expression on human peripheral blood lymphocytes in parallel with the increased lymphocyte apoptosis in SLE patients shows an inverse relation between high anti-CRP IgG titers and lymphopenia, which possibly results from the opsonization of lymphocytes expressing mCRP on their cell surfaces, thus increasing the elimination of circulating lymphocytes through the reticuloendothelial system [159].