Except for NSAIDS and other anti-inflammatory drugs that are designed to initially or partially reduce inflammation (including statins and aspirin), lipid-lowering agents, and anti-CRP drugs, one could suppose that vaccine-related induced immunity can possibly lower inflammation due to infections from pathogens, and also, immunocompromised cases may have lower CRP due to their state, thus having a deviation from certain CRP concentrations’ means of some studies [1136,1137]. This evidence concerns the gene CRP and infection.