CRP has also been assessed on penile vascular disease where there can be a slight increase (mean approx. 2 mg/L), it was also reported that epididymitis/orchitis have a greater CRP of more than 24 mg/L, whereas males with acute scrotum can show notably elevated CRP (mean 68 mg/L) [447,448,449]. This evidence concerns the gene CRP and epididymitis.