It was also identified in the frontal cortex of decayed AD cases in cortical Aβ plaques, whereas other data revealed its capacity to colocalize not only with CD68, NF-κB, and Il-1 in AD post-mortem cases, but also with both phosphorylated Tau (p-Tau) and Aβ(42) in mice [105]. The gene discussed is IL1B; the disease is Alzheimer disease.