Relatively old data reveal that serum CRP titers can be more than 3 mg/L in women with endometriosis and uterine fibroids, and other data indicate that it is a marker of clinical importance in determining possible reproductive failure, whereas a more recent study showed that following bilateral Uterine Artery Embolization (UAE) as a treatment for leiomyomas and adenomyosis, CRP concentrations can be increased (a median of approx. 80 mg/L) [395,396,397]. This evidence concerns the gene CRP and leiomyoma.