CRP and metastatic malignant neoplasm in the lymph nodes: Despite the fact that a study found no association between CRP and the risk of testicular or penile cancer, other data indicate that high preoperative serum CRP titers (>15 mg/L) have been associated with poor survival in cases with penile cancer, and also, an analysis revealed that CRP > 20 mg/L is optimal for predicting lymph node metastasis [843,844,845].