AGT and Hypertension: We next investigated possible changes in ΔD* in a model of acute transient hypertension, adapted from a mouse model in which robust decreases in PV flow were recorded, attributed to a concomitant reduction in wall motion pulsatility.4 We measured a consistent decrease in ΔD* after Ang-II-induced hypertension, where relative blood pressure increase was comparable to human hypertension defined as >110–115 mmHg,8 with no change recorded after vehicle (Figure 2).