Combined with functional annotation and signaling pathway prediction by whole transcriptome sequencing, the results showed that the relevant target genes were mainly enriched in pathways similar to systemic lupus erythematosus (SLE) immune inflammation, chronic myeloid cytopathy, and viral infection cancerous lesions (Figure 3(a) and (b)), which was why we focused more on inflammatory alterations in NMOSD myeloid immune cells, and in connection with previous literature reports, CD14+ monocytes became the breakthrough point for the next study. The gene discussed is CD14; the disease is viral infectious disease.