HLA-G and chronic kidney disease: eGFR less than 90 mL/minute/1.73m2 or a reduction of more than 25% from baseline were both considered signs of TDF-related renal impairment. For the CKD-EPI, a reduction in eGFR of more than 10 mL/minute/1.73m2 from baseline was considered to indicate decreased renal function. B2 microglobulin’s normal range was less than 0.5 mg