The role of Fibrillin-1 (FBN1) in cancer is unclear, with one study showing that MiR-133b inhibited the proliferation, migration, and invasive capacity of GC cells by increasing FBN1 expression [44], while another article found that FBN1 promotes cisplatin resistance in ovarian cancer by maintaining energy stress and inducing angiogenesis in vitro and in vivo [45]. This evidence concerns the gene FBN1 and ovarian carcinoma.