Finally, unbiased proteogenomics via CITE-seq confirmed strong correlation of cell surface CD32 (r = 0.6183783, P < 2.2 × 1016) and CD33 (r = 0.3262483, P < 2.2 × 1016) with U5 snRNP200 among AML blasts with the highest (top 10%) U5 snRNP200 expression (Fig. 7g). Here, FCGR2B is linked to acute myeloid leukemia.