Evaluation of cell surface U5 snRNP200 expression on five EVI1(also known as MECOM)-rearranged AML patient samples by high-density 36-color spectral flow cytometry as well as on three human EVI1-rearranged patient-derived AML cell lines (HNT-34, MUTZ-3 and YCU-AML1) revealed clear U5 snRNP200 surface expression on all five EVI1-rearranged patient samples as well as an overlap with CD33 and CD32A expression (Extended Data Fig. 4 and Supplementary Table 4). Here, RUNX1 is linked to acute myeloid leukemia.