The 30 genes supported by ≥3 criteria include genes involved in transcriptional regulation (BNC2, HMGA2, PHC2, TSHZ3, GLIS3), production, signaling or response to thyroid hormones (TG, TPO, TSHR, PDE4D) or non-thyroid hormones (ADCY6, INSR, NR3C2), regulation of thyroid-relevant pathways (HMGA2, IGFBP5), neuronal protection and neuropathies (ADCY6, TRIM2), angiogenesis (SMOC2, SKG1, VEGFC, SPATA13), AKT signalling (PTEN, SGK1, AKT1, PTPRS) and ciliogenesis (SDCCAG8). This evidence concerns the gene AKT1 and neuropathy.