ZNF207 and Bloom syndrome: Meanwhile, BuGZC overexpression suppressed the binding of the YT521-B promoter to BuGZ in Flag-BuGZ knock-in flies under BLM treatment, whereas BuGZCS overexpression displayed diminished effect on attenuating the binding of BuGZ to the YT521-B promotor when compared with BuGZC (Supplementary Fig. 6j).