METTL3 and non-small cell lung carcinoma: As showing in Figure 2d,e, PD-L1 was up-regulated in NSCLC cells (A549 and H1650) which were co-cultured with CAFs-CM, and METTL3-knockdown in CAFs accelerated this effect, while overexpression of -METTL3 in CAFs alleviated this effect.