Similar to anti-Spike IgG data, the anti-SARS-CoV-2 surrogate neutralizing activity was lowest in the post-LT group, and this reached significance against each of the other disease groups for the anti-Spike reference strain but only against control and cirrhosis groups for anti-RBD reference, Alpha and Delta strains, and against control for Beta and Gamma strains. This evidence concerns the gene CHMP5 and Cirrhosis.